Research Projects

Our NIH-funded research seeks to understand bacterial factors that affect infection outcomes and to translate this knowledge into novel antibacterial therapeutics.

Small colony variants from murine lung infection

Bacterial Epigenetics

Impact of DNA methylation on phenotypic heterogeneity in drug-resistant bacteria.

Pseudomonas aeruginosa biofilm overexpression the Pel polysaccharide.

Biofilm Polysaccharides

Influence of bacterial polysaccharides on treatment outcomes.

A P. aeruginosa vaccine could help prevent airway infections in people with cystic fibrosis.

Vaccine Development

Optimization of a polysaccharide vaccine to prevent or treat bacterial infections.